KDM1A Antibody

• Catalog Number: orb1731768
• Category: Antibodies
• Description: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IP, WB
• Reactivity: Hamster, Human, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human KDM1/LSD1
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 93 kDa; Observed MW: 110 kDa
• Entrez: 23028
• UniProt ID: O60341
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific
• Note: For research use only
• Expiration Date: 12 months from date of receipt.