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KD36

SKU: orb3173954

Description

KD36 is a selective KRAS-G12C inhibitor with an IC50 value of 0.92 μM. It suppresses the phosphorylation of ERK and AKT, induces the accumulation of reactive oxygen species (ROS), and reduces mitochondrial membrane potential, leading to apoptosis in KRAS-G12C mutant cells. KD36 is applicable in research related to non-small cell lung cancer (NSCLC).

Images & Validation

Key Properties

TargetPERK,Mitochondrial Metabolism,ROS,Akt,Apoptosis,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information