KBU2046

SKU: orb1308161

Description

KBU2046 is an orally bioavailable small molecule that uniquely targets chaperone heterocomplexes to modulate client protein interactions, thereby inhibiting cell motility and invasion. This mechanism suppresses metastasis in preclinical models, extending lifespan without the typical profile of classical HSP90 inhibitors, making it a valuable tool for cancer metastasis research.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1143863-69-7
• MW: 242.24
• Purity: 99.89% (May vary between batches)
• Formula: C₁₅H₁₁FO₂
• SMILES: Fc1ccc(cc1)C1COc2ccccc2C1=O
• Target: HSP,Others
• Solubility: DMSO:45 mg/mL (185.77 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, KBU 2046, KBU2046, KBU-2046, inhibit

Compound Identifiers

PubChem CID

25227426