KB02-SLF

SKU: orb1988268

Description

KB02-SLF is a molecular glue-type PROTAC that induces nuclear FKBP12 degradation by covalently engaging the E3 ligase DCAF16. This compound is used in chemical biology and targeted protein degradation research to study FKBP12 function in both cellular and in vivo models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• MW: 949.52
• Formula: C₅₀H₆₅ClN₄O₁₂
• SMILES: O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCOCCOCCNC(COC3=CC4=C(N(C(CCl)=O)CCC4)C=C3)=O)=O)=C2)CCC5=CC=C(OC)C(OC)=C5
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137347727