KAT6-IN-4

SKU: orb3173054

Description

KAT6-IN-4 (Compound Example 2) is a selective inhibitor of lysine acetyltransferase 6 (KAT6). It inhibits the transcription of oncogenes such as ERα. In ER+/HER2- breast cancer xenograft models, KAT6-IN-4 demonstrates strong antitumor activity. This compound holds promise for research into KAT6-driven malignancies, such as breast cancer and non-small cell lung cancer.

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 2901797-38-2
• MW: 470.5
• Formula: C₂₂H₂₂N₄O₆S
• SMILES: O=S(=O)(NC1=NOC2=CC(=C3C(OCCC3)=C21)CN4N=CC=C4)C=5C(OC)=CC=CC5OC
• Target: Histone Acetyltransferase,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histone Acetyltransferase,Estrogen Receptor/ERR