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KAN0438757

SKU: orb1309514

Description

KAN0438757 is a potent and selective PFKFB3 kinase inhibitor, exhibiting an IC50 of 0.19 µM. It is a valuable research tool for studying cancer metabolism and has demonstrated utility in both in vitro cellular assays and in vivo tumor model studies.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number1451255-59-6
MW447.43
Purity99.80% (May vary between batches)
FormulaC21H18FNO7S
SMILESOCCOC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)cc1O
TargetGlucokinase,Autophagy
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.38 mM);DMSO:130 mg/mL (290.55 mM)

Bioactivity

Target IC50
PFKFB3:0.19 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, KAN0438757, KAN-0438757, KAN 0438757, Autophagy, PFKFB3

Similar Products

  • KAN0438757 [orb1218795]

    >98% (HPLC)

    1451255-59-6

    447.43

    C21H18FNO7S

    10 mg, 5 mg, 50 mg, 100 mg, 25 mg, 500 mg, 1 g, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 150.00
5 mg
$ 250.00
1 ml x 10 mM (in DMSO)
$ 260.00
10 mg
$ 370.00
25 mg
$ 630.00
50 mg
$ 850.00
100 mg
$ 1,130.00
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