Kamebanin

SKU: orb1297100

Description

Kamebanin is a natural diterpenoid with demonstrated antibacterial properties. It exhibits potent cytotoxic effects against HeLa and HL-60 cell lines in vitro, making it a compound of interest for oncology and infectious disease research.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 39388-57-3
• MW: 334.45
• Purity: 98.00% (May vary between batches)
• Formula: C₂₀H₃₀O₄
• SMILES: OC1[C@@]23[C@]([C@@]4(C)[C@](C[C@H]2O)(C(C)(C)CC[C@@H]4O)[H])(CC[C@]1(C(=C)C3=O)[H])[H]
• Target: Antifection

Bioactivity

• In Vitro:
  Fifteen Isodon diterpenoids (1-15) were evaluated for their cytotoxic activity against HeLa and HL-60 human cancer cell lines, and against murine vincristine (VCR)-resistant P388 cells. CONCLUSIONS: Kamebanin (14) showed efficient cytotoxic activity against HeLa and HL-60 cells. In addition, although dihydroenmein (2) and trichorabdal B (7) were inactive against several tested cell types, they were found to have cytotoxic-enhancing activity of VCR against VCR-resistant P388 cells.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Kamebanin, Antifection

Compound Identifiers

PubChem CID

168476199