KAL-21404358

SKU: orb1737975

Description

KAL-21404358 is a novel allosteric inhibitor targeting the P110 site of K-RasG12D. This binding disrupts the K-RasG12D/B-Raf interaction, thereby inhibiting downstream RAF-MEK-ERK and PI3K-AKT signaling pathways. It is a valuable research tool for investigating Ras-driven cancers in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1065573-84-3
• MW: 357.49
• Formula: C₂₁H₃₁N₃O₂
• SMILES: OC=1C2=C(N=C(CN3CC(CCO)N(CC(C)(C)C)CC3)C1)C=CC=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45185414