K882

SKU: orb2944660

Description

K882 (Compound 4e) is a potent Src inhibitor (K_D = 0.315 µM) that induces apoptosis and suppresses key survival proteins and oncogenic pathways, including PI3K/Akt/mTOR. It demonstrates antitumor efficacy in non-small cell lung cancer models in both cellular and in vivo studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• MW: 292.33
• Formula: C₁₈H₁₆N₂O₂
• Target: mTOR,Src,Ras,Akt,STAT,Kras,Apoptosis,p38 MAPK,Survivin,IAP,JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

mTOR,Src,Ras,Akt,STAT,Kras,Apoptosis,p38 MAPK,Survivin,IAP,JAK