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K20

SKU: orb1686214

Description

K20 is a potent and selective KRas G12C inhibitor (IC50: 1.16 nM) demonstrating in vitro anticancer activity in H358 cells (IC50: 0.78 μM) and in vivo tumor growth inhibition (TGI: 41%). It induces apoptosis by reducing Erk phosphorylation, making it a valuable tool for oncology and signal transduction research.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW543.34
FormulaC24H20Cl2F4N4O2
TargetKras,Ras,ERK,Apoptosis,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Protocol Information