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K11
Catalog Number: orb2277096
| Catalog Number | orb2277096 |
|---|---|
| Category | Small Molecules |
| Description | K11, an antimicrobial peptide, demonstrates activity against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL) and inhibits bacterial biofilm formation. It also acts synergistically with various antibiotics (Chloramphenicol, Meropenem, Rifampicin, etc.) to combat drug-resistant K. pneumoniae and exhibits high thermal and wide pH stability. |
| MW | 2493.09 |
| CAS Number | 1398109-79-9 |
| Formula | C123H198N32O23 |
| SMILES | C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CO)=O)CCCCN)=O)NC([C@H](CCCCN)N)=O)C=5C=6C(NC5)=CC=CC6 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 3
Acetyl-HIST1H2BC (K11) Antibody [orb516990]
ChIP, ELISA, IHC, WB
Human
Rabbit
Polyclonal
Unconjugated
50 μl, 100 μl - Item 1 of 3
Acetyl-H2AFZ (K11) Antibody [orb416602]
ChIP, ELISA, IF, WB
Human
Rabbit
Polyclonal
Unconjugated
50 μl, 100 μl - Item 1 of 2
Crotonyl-HIST1H2BC (K11) Antibody [orb516360]
ELISA, IF, WB
Human
Rabbit
Polyclonal
Unconjugated
50 μl, 100 μl - Item 1 of 3
Histone H2B (Acetyl K11) Mouse Monoclonal Antibody [orb1152019]
WB
Rat
Human, Mouse
Mouse
Monoclonal
Unconjugated
100 μl, 25 μl - Item 1 of 1
β-hydroxybutyryl-HIST1H2BC (K11) Antibody [orb517014]
ELISA, WB
Human
Rabbit
Polyclonal
Unconjugated
50 μl, 100 μl
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
