K-Ras(G12C) inhibitor 6

SKU: orb1303842

Description

This small molecule is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant. It achieves complete target occupancy in vitro and is a key tool for investigating mutant KRAS-driven oncology in both cellular and animal model studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2060530-16-5
• MW: 405.34
• Purity: 100.00%
• Formula: C₁₇H₂₂Cl₂N₂O₃S
• SMILES: C(COC1=C(Cl)C=C(Cl)C=C1)(=O)N2CCC(NC(CCCS)=O)CC2
• Target: Raf,Ras
• Solubility: DMSO:73 mg/mL (180.1 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

K Ras(G12C) Inhibitor 6, K-Ras, KRas(G12C) Inhibitor 6, K-Ras(G12C) inhibitor 6, K-Ras(G12C) Inhibitor 6, K-Ras(G-12C) Inhibitor 6, inhibit, Inhibitor, Ras

Compound Identifiers

PubChem CID

71815954