K-Opioid receptor agonist-1

• Catalog Number: orb2564488
• Category: Small Molecules
• Description: K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.
• Purity: 98.00%
• MW: 454.39
• CAS Number: 1816990-29-0
• Formula: C₂₂H₂₉Cl₂N₃O₃
• SMILES: C(CC1=CC(Cl)=C(Cl)C=C1)(=O)N2[C@]3([C@@](N(C(OC)=O)CC2)(CCC[C@@H]3N4CCCC4)[H])[H]
• Storage: -20°C
• Note: For research use only