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JZ19

SKU: orb3028951

Description

JZ19 reduces intracellular levels of LDH and ROS and demonstrates antioxidant activity against oxygen-glucose deprivation (OGD)-induced myocardial cell damage. It reverses Isoproterenol-induced myocardial cell hypertrophy and apoptosis through the PI3K-AKT-GSK3β signaling pathway. Additionally, JZ19 alleviates Isoproterenol-induced heart failure in mouse models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetPI3K,Akt,GSK-3,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information