JYQ-164

SKU: orb3134424

Description

JYQ-164 is a small‑molecule inhibitor targeting human Parkinson’s disease protein 7 (PARK7/DJ‑1) with an IC50 value of 21 nM. It exerts its inhibitory effect by covalently and selectively targeting the key residue Cys106 of PARK7, and its inhibitory activity against PARK7 is approximately 5‑fold higher than that of the previously reported inhibitor JYQ‑88. JYQ-164 can be used in studies related to the mechanisms of Parkinson’s disease and cancer .

Key Properties

• MW: 530.62
• Formula: C₂₃H₂₆N₆O₅S₂
• SMILES: O=C(NC1=NC2=C(CN(C(C3=CC(S(=O)(N4CCOCC4)=O)=CC=C3)=O)CC2)S1)[C@H]5CN(C#N)CC5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Others