JY-1-106

SKU: orb1985919

Description

JY-1-106 is a small molecule BH3 α-helix mimetic that promotes apoptosis in cancer cells, including lung and colon carcinomas, by inhibiting the anti-apoptotic proteins Bcl-xL and Mcl-1. Its mechanism involves disrupting their protective interactions with the pro-apoptotic protein Bak. This compound is a valuable research tool for studying Bcl-2 family protein dynamics and apoptosis induction in both in vitro and in vivo cancer models.

Key Properties

• MW: 550.61
• Formula: C₂₉H₃₄N₄O₇
• SMILES: O=C(O)C1=CC=C(NC(C2=NC(OC(C)C)=C(NC(C3=CC=C(N)C(OC(C)C)=C3)=O)C=C2)=O)C(OC(C)C)=C1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57338853