JTK-109

SKU: orb1700266

Description

JTK-109 is a small molecule inhibitor targeting the hepatitis C virus NS5B RNA-dependent RNA polymerase. It demonstrates inhibitory activity against HCV genotypes 1b and 3a in subgenomic replicon assays and against recombinant enzymes. This compound is a valuable tool for antiviral research in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 480462-62-2
• MW: 638.13
• Purity: 99.68% (May vary between batches)
• Formula: C₃₇H₃₃ClFN₃O₄
• SMILES: FC1=C(C=2N(C=3C(N2)=CC(C(O)=O)=CC3)C4CCCCC4)C=CC(OCC5=C(C=CC(=C5)N6C(=O)CCC6)C7=CC=C(Cl)C=C7)=C1
• Target: HCV Protease
• Solubility: DMSO:6.39 mg/mL (10.01 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HCV Protease, HCVProtease, JTK109, JTK-109, JTK 109, NS5B polymerase

Compound Identifiers

PubChem CID

11686018