JT010

SKU: orb1308170

Description

JT010 is a potent and selective TRPA1 channel agonist with a sub-nanomolar EC50 of 0.65 nM. This small molecule is a valuable research tool for studying TRPA1-mediated signaling in pain, inflammation, and respiratory pathways in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 917562-33-5
• MW: 354.85
• Purity: 99.75% (May vary between batches)
• Formula: C₁₆H₁₉ClN₂O₃S
• SMILES: COCCCN(C(=O)CCl)c1nc(cs1)-c1ccc(OC)cc1
• Target: TRP/TRPV Channel
• Solubility: DMSO:50 mg/mL (140.9 mM)

Bioactivity

• Target IC50:
  TRPA1:0.65 nM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

JT 010, JT010, JT-010, inhibit, Inhibitor, Transient receptor potential channels, TRP Channel, TRPChannel, TRPA1, TRPV Channel, TRPVChannel

Compound Identifiers

PubChem CID

18524489