JQEZ5

SKU: orb1299936

Description

JQEZ5

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1913252-04-6
• MW: 542.68
• Purity: 98.14%
• Formula: C₃₀H₃₈N₈O₂
• SMILES: CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(nc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(C)CC1
• Target: Histone Methyltransferase
• Solubility: DMSO:25 mg/mL (46.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.69 mM)

Bioactivity

• In Vitro:
  JQEZ5 inhibits colony formation of primary human CD34+ chronic myelogenous leukemia (CML) stem/progenitor cells but not non-cancerous human CD34+ hematopoietic stem/progenitor cells when used at concentrations ranging from 0.5 to 5 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, JQEZ 5, JQEZ5, JQEZ-5, methionine, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, EZH2, H3K27me3, antitumor, PRC2, S-adenosyl

Compound Identifiers

PubChem CID

121322599