JNK-IN-23

SKU: orb3135339

Description

JNK-IN-23 (Compound K12) is an inhibitor of JNK. It effectively inhibits the proliferation of MDA-MB-231 cells with a GIC50 of 30 nM. In vivo, JNK-IN-23 blocks metastatic growth of triple-negative breast cancer (TNBC). Additionally, it suppresses the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and the pyruvate dehydrogenase complex (PDHC).

Research Area

Signal Transduction

Key Properties

• CAS Number: 1007786-48-2
• MW: 382.50
• Formula: C₁₉H₁₈N₄OS₂
• SMILES: O=C1N=C(NC=2SC(=C(C12)C)C)C(SC=3N=C4C=CC=CC4=NC3C)C
• Target: JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

JNK