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JNK-IN-14

SKU: orb2277712

Description

JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits beclin-1 production in K562 leukemia cells, demonstrating greater inhibitory efficacy than SP600125.

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Key Properties

MW521.63
FormulaC27H31N5O4S
TargetCytochromes P450,JNK

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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JNK-IN-14 (orb2277712)

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