JNK-IN-11

SKU: orb1689491

Description

JNK-IN-11 is a potent, pan-JNK inhibitor with IC50 values of 1.8 µM (JNK1), 21.4 µM (JNK2), and 2.2 µM (JNK3). This cell-permeable compound is a valuable research tool for investigating JNK signaling in immune dysfunction, neuronal apoptosis, and inflammatory diseases in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 676594-38-0
• MW: 281.35
• Purity: 99.24% (May vary between batches)
• Formula: C₁₂H₁₁NO₃S₂
• SMILES: O=C(OC)C=1SC=CC1NC(=O)CC=2SC=CC2
• Target: JNK

Bioactivity

• Target IC50:
  JNK1:1.8 μM|JNK2:21.4 μM|JNK3:2.2 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

JNK

Compound Identifiers

PubChem CID

2808202