JNK-1-IN-5

SKU: orb2945472

Description

JNK-1-IN-5 (Compound 14) is a sub-nanomolar potent and selective JNK1 inhibitor. It blocks TGF-β-induced epithelial-mesenchymal transition in vitro and has demonstrated anti-fibrotic efficacy in animal models of pulmonary fibrosis, supporting its use in fibrotic disease research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3047794-08-8
• MW: 509.355
• Formula: C₂₃H₂₁BrN₆O₃
• SMILES: O=C(N)C=1C=CC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)C(=O)N4CC5OCC4C5
• Target: JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677418