JNJ525

SKU: orb1986918

Description

JNJ525 is a small molecule TNFα inhibitor that acts via an aggregation-based mechanism, blocking its interaction with TNFR1 and TNFR2 with IC₅₀ values of ~1.2 µM and ~1.1 µM, respectively, as measured by TR-FRET. It is a useful research tool for studying TNFα signaling in both cellular and biochemical assays.

Key Properties

• MW: 514.64
• Formula: C₃₁H₃₀N₈
• SMILES: NC1=NC=CC(N(CC2=CC=CC=C2)C(C=CC=C3)=C3C4=CC=CC(C5=CN=C(N6CCNCC6)N=C5)=C4)=N1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124222736