JNJ-61803534

SKU: orb1739415

Description

JNJ-61803534 is a potent and orally bioavailable RORγt inverse agonist. It inhibits IL-17A production in human Th17 cells with an IC50 of 9.6 nM, demonstrating anti-inflammatory activity. This compound is a valuable tool for researching Th17-driven pathologies such as psoriasis and autoimmune diseases in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1917306-14-9
• MW: 622.41
• Formula: C₂₃H₂₃Cl₂F₆N₃O₄S
• SMILES: C[C@@H]1CCCN1C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(=O)NCC(C)(C)O
• Target: ROR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121303394