JMX0293

SKU: orb1744186

Description

JMX0293 is a potent and selective STAT3 phosphorylation inhibitor with strong anti-tumor activity. It induces apoptosis in triple-negative breast cancer MDA-MB-231 cells in vitro (IC50 = 3.38 µM) and suppresses xenograft tumor growth in vivo, while exhibiting minimal toxicity to non-cancerous MCF-10A breast epithelial cells.

Research Area

Cell Biology

Key Properties

• MW: 569.43
• Formula: C₂₅H₃₀Cl₂N₄O₇
• SMILES: CC(OC(NCCOC1=C(C=C(C=C1)Cl)C(N[C@@H](C(C)C)C(NC2=C(C=C(C=C2)[N+]([O-])=O)Cl)=O)=O)=O)(C)C
• Target: Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168280225