iJMJD6

SKU: orb1297784

Description

WL12 (ZINC6733033) is a first-in-class, small-molecule inhibitor of JMJD6. It has demonstrated efficacy in suppressing cancer cell proliferation in vitro, notably in cervical and liver cancer models, by targeting JMJD6-dependent pathways. This compound serves as a valuable research tool for oncology and epigenetics studies.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 899548-78-8
• MW: 277.3
• Purity: >98%
• Formula: C₁₆H₁₁N₃O₂
• SMILES: O=C1C(=CC=2C(O1)=CC=C(C)C2)C=3NC=4C(N3)=CN=CC4
• Target: Protein demethylase
• Solubility: Soluble in DMSO (up to 12 mg/ml with warming)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

WL12

Compound Identifiers

PubChem CID

22424483