JMJD6 inhibitor WL12

SKU: orb1297784

Description

WL12 (ZINC6733033) is a first-in-class, small-molecule inhibitor of JMJD6. It has demonstrated efficacy in suppressing cancer cell proliferation in vitro, notably in cervical and liver cancer models, by targeting JMJD6-dependent pathways. This compound serves as a valuable research tool for oncology and epigenetics studies.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 899548-78-8
• MW: 277.28
• Purity: 99.63% (May vary between batches)
• Formula: C₁₆H₁₁N₃O₂
• SMILES: O=C1C(=CC=2C(O1)=CC=C(C)C2)C=3NC=4C(N3)=CN=CC4
• Target: Histone Demethylase,Others
• Solubility: DMSO:2.78 mg/mL (10.03 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-, JMJD6 inhibitor WL12, ZINC6733033, ZINC-6733033, ZINC 6733033

Compound Identifiers

PubChem CID

22424483