JJH260

SKU: orb1692304

Description

JJH260 is a potent inhibitor of the FAHFA hydrolase AIG1 (IC50 = 0.57 µM against 9-PAHSA hydrolysis) and also targets ADTRP, ABHD6, LYPLA1, and LYPLA2. This cell-permeable compound effectively blocks FAHFA hydrolase activity in lysates and intact cells, such as LNCaP and T cells, making it a valuable chemical probe for studying lipid signaling in metabolic and immunological research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1831135-30-8
• MW: 568.06
• Formula: C₂₉H₃₄ClN₅O₅
• SMILES: O=C1C2N(C(=O)N1OC(=O)N3CCC(CCC4=CC=C(Cl)C=C4)CC3)CCN(C(=O)C5=CC=C(N(C)C)C=C5)C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71710928