JBJ-08-178-01

SKU: orb2665315

Description

JBJ-08-178-01 is a mutant-selective HER2 tyrosine kinase inhibitor that induces proteasomal degradation of the receptor, reducing its kinase activity and protein levels. It has demonstrated antitumor activity in non-small cell lung cancer research, showing promise in both in vitro and in vivo experimental models.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 2401867-58-9
• MW: 562.62
• Formula: C₃₁H₃₀N₈O₃
• SMILES: N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(C)=C(OC4=CC=5N(C=C4)N=CN5)C=C3
• Target: Others,Proteasome

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155776785