Janagliflozin

SKU: orb3174263

Description

Janagliflozin is an orally active and highly selective inhibitor of sodium-glucose co-transporter protein 2 (SGLT2) with an IC50 value of 0.0058 μM, and an IC50 of 4.802 μM for SGLT1. It inhibits SGLT2 in the proximal renal tubules, reducing glucose reabsorption and promoting urinary glucose excretion (UGE), thereby lowering blood glucose levels. Janagliflozin holds potential for research in treating type 2 diabetes.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1800115-22-3
• MW: 460.95
• Formula: C₂₅H₂₉ClO₆
• SMILES: O([C@@H]1C[C@@]2([C@@](C2)(C1)[H])[H])C3=CC=C(CC4=CC(=CC=C4Cl)[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C=C3
• Target: SGLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SGLT