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JAK3/BTK-IN-7

SKU: orb2565926

Description

XL-12 (JAK3/BTK-IN-7) is a potent dual inhibitor of JAK3 (IC50=2 nM) and BTK (IC50=14 nM). It is a research tool for investigating autoimmune and inflammatory diseases, including rheumatoid arthritis, in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2844387-16-0
MW554.6
FormulaC29H30N8O4
SMILESNC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=C5C(=C(NC(=O)C6=CC=C(N(C)C)C=C6)C=C4)OCO5
TargetJAK,BTK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information