JAK2-IN-4

SKU: orb1709374

Description

JAK2-IN-4 is a potent and selective small molecule inhibitor targeting JAK2 and JAK3 kinases, exhibiting IC50 values of 0.7 nM and 23.2 nM, respectively. It is a valuable research tool for investigating JAK-STAT signaling in hematological malignancies and immune disorders in both cellular and animal models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1438284-00-4
• MW: 469.56
• Formula: C₂₃H₂₇N₅O₄S
• SMILES: CC=1C(C2=CC3=C(O2)CCN(S(C)(=O)=O)C3)=NC(NC4=CC=C(C=C4)N5CCOCC5)=NC1
• Target: JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

76072368