JA2131

SKU: orb1744135

Description

JA2131 is a potent small molecule PARG inhibitor (IC50 = 0.4 µM) that disrupts DNA damage repair. It is used in cancer research to study replication fork dynamics and PARP inhibitor resistance, demonstrating cytotoxic effects in cellular models.

Research Area

Cell Biology

Key Properties

• CAS Number: 6505-99-3
• MW: 341.45
• Formula: C₁₃H₁₉N₅O₂S₂
• SMILES: S=C1C2=C(N=C(SCCN3CCOCC3)N2)N(C)C(=O)N1C
• Target: Others,Poly(ADP-ribose) Glycohydrolase (PARG)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

4361023