J-104871

SKU: orb1703340

Description

J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase inhibitor that competitively inhibits Ras farnesylation. It blocks Ras processing in H-ras-transformed NIH3T3 cells in vitro and demonstrates antitumor efficacy in corresponding nude mouse xenograft models in vivo, supporting cancer research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 191088-19-4
• MW: 708.67
• Purity: 99.03% (May vary between batches)
• Formula: C₃₈H₃₂N₂O₁₂
• SMILES: C(O)(=O)C1(C(O)=O)O[C@H](C(N([C@@H]([C@H](C/C=C/C2=NC=3C(O2)=CC=CC3)C=4C=C5C(=CC4)OCO5)C)CC6=CC7=C(C=C6)C=CC=C7)=O)[C@H](C(O)=O)O1
• Target: Ras,Transferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9962301