Ivermectin B1a

SKU: orb1306221

Description

Ivermectin B1a is the principal component of commercial ivermectin, derived from Avermectin B1a. It is widely used in research to study antiparasitic mechanisms and modulate glutamate-gated chloride channels in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 71827-03-7
• MW: 875.09
• Purity: 96.18% (May vary between batches)
• Formula: C₄₈H₇₄O₁₄
• SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C
• Target: Parasite,SARS-CoV
• Solubility: DMSO:100 mg/mL (114.27 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.57 mM)

Bioactivity

• In Vitro:
  Ivermectin B1a(0.3 μg/ml) is inactive, whereas in the case of the minor component, ivermectin B1b(0.3 μg/ml) produces 100% mortality of snails.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COVID-19, Avermectin, B1a, anti-parasite, Parasite, Ivermectin, Ivermectin B1a, inhibit, Inhibitor, SARS-CoV, SARSCoV, SARS coronavirus, SARS-CoV-2

Compound Identifiers

PubChem CID

6071412