Ivaltinostat formic

SKU: orb1686967

Description

Ivaltinostat (CG-200745) formic is an orally bioavailable pan-HDAC inhibitor that induces histone and tubulin hyperacetylation, leading to p53 activation, cell cycle arrest, and apoptosis. It demonstrates antitumor activity and can reverse chemoresistance to agents like Gemcitabine and 5-FU in preclinical cancer models, both in vitro and in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• MW: 473.56
• Formula: C₂₅H₃₅N₃O₆
• Target: HDAC,MDM-2/p53,Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,MDM-2/p53,Apoptosis,Others