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ITA-5

SKU: orb3173468

Description

ITA-5 is a TBK1 inhibitor based on an itaconic acid structure. It significantly suppresses IFN-β secretion and inhibits the phosphorylation of TBK1, IRF3, and STAT1. ITA-5 is useful for research in autoimmune diseases and excessive inflammation.

Images & Validation

Key Properties

CAS Number2374162-36-2
MW305.33
FormulaC16H19NO5
SMILES[C@@H](CC1=CC=CC=C1)(NC(C(CC(OC)=O)=C)=O)C(OC)=O
TargetSTAT,IκB/IKK,IFNAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information