ISRIB (trans-isomer)

SKU: orb1226075

Description

ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.

Key Properties

• CAS Number: 1597403-47-8
• MW: 451.34
• Purity: >98% (HPLC)
• Formula: C₂₂H₂₄Cl₂N₂O₄
• SMILES: O=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
• Target: ERK
• Solubility: DMSO:4 mg/mL (8.86 mM); Ethanol:<1 mg/mL (<1 mM); Water：<1 mg/mL (<1 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

trans-ISRIB

Quick Database Links

Gene Symbol

ERK