Isoviolanthin

SKU: orb1308800

Description

Isoviolanthin, a flavonoid glycoside from Dendrobium officinale leaves, inhibits migration and invasion in TGF-β1-stimulated hepatocellular carcinoma (HCC) cells in vitro while showing no cytotoxicity to normal hepatocytes. This suggests its research potential for investigating metastatic HCC mechanisms and therapeutic strategies.

Research Area

Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 40788-84-9
• MW: 578.52
• Purity: 99.66% (May vary between batches)
• Formula: C₂₇H₃₀O₁₄
• SMILES: C[C@@H]1O[C@H]([C@H](O)[C@H](O)[C@H]1O)c1c(O)c([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2oc(cc(=O)c2c1O)-c1ccc(O)cc1
• Target: Others,TGF-beta/Smad,PI3K,mTOR,Akt,Histone Demethylase,MMP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.46 mM);DMSO:60 mg/mL (103.71 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

hepatocellular carcinoma cells cytotoxic effects, Inhibitor, normal liver LO2 cells, inhibit, Isoviolanthin, Transforming growth factor beta, TGF-β1 EMT, TGF-beta/Smad

Compound Identifiers

PubChem CID

101422758