Isoschaftoside

SKU: orb1303591

Description

Isoschaftoside

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 52012-29-0
• MW: 564.49
• Purity: 99.88%
• Formula: C₂₆H₂₈O₁₄
• SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)c([C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)c(O)c2c1oc(cc2=O)-c1ccc(O)cc1
• Target: p62,Autophagy,Anti-infection,ROS,Antifungal,Parasite
• Solubility: DMSO:50 mg/mL (88.58 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.54 mM)

Bioactivity

• In Vitro:
  METHODS AND RESULTS:In East African small-holder farming of maize, the cattle forage legume, Desmodium uncinatum is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Bioassay-guided fractionation of the root extract of D. uncinatum revealed Isoschaftoside to be the main compound in the most potent fraction inhibiting growth of germinated S. hermonthica radicles. Bioassays repeated with Isoschaftoside isolated from a different plant source, Passiflora incarnata, proved it to be a biologically active component. CONCLUSIONS: Analysis of the root exudates produced by hydroponically grown D. uncinatum showed Isoschaftoside to be present in the hydroponic media at biologically active concentrations of 10-100 nM.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-infection, Antiinfection, Antifection, Inhibitor, Fungal, Isoschaftoside, inhibit

Compound Identifiers

PubChem CID

3084995