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Isomangiferin

SKU: orb1225527

Description

Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.

Images & Validation

Key Properties

CAS Number24699-16-9
MW422.3396
Purity>98% (HPLC)
FormulaC19H18O11
SMILESC1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
TargetiGluR
SolubilityDMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • Isomangiferin [orb1303582]

    98.84% (May vary between batches)

    24699-16-9

    422.34

    C19H18O11

    10 mg, 1 mg, 5 mg, 25 mg, 50 mg, 1 ml x 10 mM (in DMSO), 2 mg
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Isomangiferin (orb1225527)

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Available Sizes

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100 mg
200 mg
500 mg
5 mg
$ 190.00
10 mg
$ 290.00
25 mg
$ 450.00
50 mg
$ 660.00