Isoetharine mesylate salt

SKU: orb1221213

Description

Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.(In Vitro):Isoetharine mesylate (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells.(In Vivo):Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model.

Key Properties

• CAS Number: 7279-75-6
• MW: 335.42
• Purity: >98% (HPLC)
• Formula: C₁₄H₂₅NO₆S
• SMILES: CS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1
• Target: Adrenergic Receptor
• Solubility: DMSO:199.7 mM;Water:199.7 mM

Bioactivity

• In Vivo:
  Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model.
• In Vitro:
  Isoetharine mesylate (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Isoetarine mesilate

Quick Database Links

Gene Symbol

Adrenergic Receptor