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Isobarbaloin

SKU: orb1310868

Description

Isobarbaloin

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number5133-19-7
MW418.39
Purity100.00% (May vary between batches)
FormulaC21H22O9
SMILESO=C1C2=C(C=CC=C2O)[C@H]([C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C4=CC(CO)=CC(O)=C14
TargetTyrosinase
SolubilityH2O:1 mg/mL (2.39 mM);DMSO:83 mg/mL (198.38 mM);Ethanol:2 mg/mL (4.78 mM)

Bioactivity

In Vivo
In the MCF-7 cell line, Aloin diminishes the proportion of cells in mitosis by inducing apoptosis, suppresses the expression of topoisomerase IIα, and downregulates cyclin B1 protein expression. In HeLaS3 cells, Aloin exhibits significant antiproliferative effects at physiological concentration (IC50=97 μM), leading to cell cycle arrest in the S phase and a marked increase in apoptosis.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Aloin, Aloin-A, Barbaloin-A, Isobarbaloin, tyrosinase

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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10 mg
$ 70.00
25 mg
$ 80.00
50 mg
$ 100.00
100 mg
$ 140.00
500 mg
$ 260.00
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