(Iso)-Z-VAD(OMe)-FMK

SKU: orb2695134

Description

(Iso)-Z-VAD(OMe)-FMK is an isomeric form of the irreversible pan-caspase inhibitor Z-VAD(OMe)-FMK, which also covalently inhibits the deubiquitinating enzyme UCHL1. This compound is widely used in apoptosis and neurobiology research, applicable in both in vitro and in vivo experimental models to study cell death and protein degradation pathways.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• Target: Caspase
• CAS Number: 634911-81-2
• MW: 467.49
• Purity: 97.10% (May vary between batches)
• Formula: C₂₂H₃₀FN₃O₇
• SMILES: C(NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@@H](C)C)=O)C)=O)(CC(OC)=O)C(CF)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Caspase, ZVAD(OH)FMK

Compound Identifiers

PubChem CID

5497173