Isepamicin sulfate

SKU: orb1300669

Description

Isepamicin sulfate is an aminoglycoside antibiotic that binds to the bacterial 30S ribosomal subunit, inhibiting protein synthesis. It is notably effective against bacteria expressing AAC(6')-I type acetyltransferase. This compound is used in research to study antibiotic resistance mechanisms and bacterial protein synthesis in vitro.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 67814-76-0
• MW: 667.68
• Purity: 98.58% (May vary between batches)
• Formula: C₂₂H₄₃N₅O₁₂·SH₂O₄
• SMILES: OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@@H](C[C@H](N)C(O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)NC(=O)[C@@H](O)CN)OC[C@]1(C)O
• Target: Antibacterial,Antibiotic
• Solubility: DMSO:Insoluble;H2O:10 mM

Bioactivity

• Target IC50:
  30S ribosomal subunit (bacterial):
• In Vitro:
  Isepamicin might be active in vitro against Gram-negative bacteria with resistance to amikacin and other aminoglycosides. The antibacterial spectrum of Isepamicin Sulphate includes Enterobacteriaceae and staphylococci, anaerobes, neisseriaceae and streptococci are resistant.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibiotic, Antibacterial, Bacterial, inhibit, Isepacin, Isepamicin, Isepamicin Sulfate, Isepamicin sulfate, Isepamicin Sulphate, Isepamicine (Isepamycin, Inhibitor, Sch21420, Sch-21420, sch21420) Sulphate, Sch 21420

Compound Identifiers

PubChem CID

71306970