Isavuconazole

SKU: orb1305740

Description

Isavuconazole (BAL-4815) is the active moiety of the prodrug isavuconazonium sulfate (BAL8557), a broad-spectrum triazole antifungal. It demonstrates potent in vitro activity against Candida species, with MIC values ranging from ≤0.004 mg/L for C. albicans to 0.5 mg/L for C. glabrata. This agent is widely used in research models to study invasive fungal infections and antifungal efficacy.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 241479-67-4
• MW: 437.47
• Purity: 98.00% (May vary between batches)
• Formula: C₂₂H₁₇F₂N₅OS
• SMILES: [C@@]([C@@H](C)C1=NC(=CS1)C2=CC=C(C#N)C=C2)(CN3C=NC=N3)(O)C4=C(F)C=CC(F)=C4
• Target: Cytochromes P450|||Antibiotic|||Antifungal
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.57 mM);DMSO:250 mg/mL (571.47 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, Fungal, fungi, ergosterol, Isavuconazole, inhibit, molds, dimorphic, CYPs, Cytochrome P450, Antibiotic, Antifungal, BAL 4815, BAL4815, BAL-4815, biosynthesis, triazole, RO0094815, RO-0094815, RO 0094815, yeasts, prodrug

Compound Identifiers

PubChem CID

6918485