IRL-1038 TFA

SKU: orb2308666

Description

IRL-1038 TFA is a potent and selective endothelin B (ETB) receptor antagonist. It blocks ETB-mediated vasodilation and is a valuable research tool for investigating cardiovascular pathologies, including in studies of vascular tone and endothelial function in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Endothelin Receptor
• Molecular Weight: 1523.7
• Purity: 98.79%
• Formula: C₇₀H₉₃F₃N₁₄O₁₇S₂
• SMILES: O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC1)N)=O)C(C)C)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)N[C@@H](CC4=CN=CN4)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

• Storage: keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IRL-1038 TFA(144602-02-8 Free base), IRL1038TFA(144602028Freebase), ET-B, Endothelin Receptor, EndothelinReceptor

Compound Identifiers

PubChem CID

145707487