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Irisolidone

SKU: orb1218353

Description

Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.

Images & Validation

Key Properties

CAS Number2345-17-7
MW314.29
Purity>98% (HPLC)
FormulaC17H14O6
SMILESO=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=C(OC)C(O)=C13
TargetChloride Channel
SolubilityDMSO:10 mM

Bioactivity

In Vitro
Irisolidone, an isoflavone metabolite, represses JC virus gene expression via inhibition of Sp1 binding in human glial cells. Irisolidone can inhibit endothelial cell proliferation.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Available Sizes

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200 mg
500 mg
5 mg
$ 440.00
10 mg
$ 660.00
25 mg
$ 1,070.00
50 mg
$ 1,480.00
100 mg
$ 1,990.00