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Catalog Number | orb1300959 |
---|---|
Category | Small Molecules |
Description | Irinotecan |
CAS Number | 97682-44-5 |
Purity | 99.92% |
MW | 586.68 |
SMILES | C(C)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(OC(=O)N6CCC(CC6)N7CCCCC7)=CC5 |
Formula | C33H38N4O6 |
Biological Activity | Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
136572-09-3 |
[136572-09-3] | |
677.19 | |
C33H45ClN4O9 E |
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