IRE1a-IN-1

SKU: orb2564484

Description

IRE1a-IN-1 (Compound 10) is a potent small molecule inhibitor of IRE1α, demonstrating an IC50 of <100 nM against XBP1 mRNA splicing. It is widely used in cancer research to study endoplasmic reticulum stress pathways in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 3033375-01-5
• MW: 407.36
• Formula: C₂₀H₁₉F₂NO₆
• SMILES: O=CC=1C(O)=C2OCCCC2=C3C1OC(=O)C(=C3C)CC(=O)N4CCC(F)(F)C4
• Target: IRE1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171491373